Musculoskeletal Health (Formerly Physical Therapy)

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Dr. Jean St-Louis
MD, FRCP(C)

Dr. Jean St-Louis obtained his medical degree at McGill University. He completed his fellowship in hematology and oncology, at the Université de Montréal and Memorial Sloan-Kettering Cancer Center. Dr. Jean-St-Louis is an active member of the hemato-oncology service at Hôpital Maisonneuve-Rosemont, in Montreal and an associate professor in the department of medicine at the University of Montreal. He is co-director of the Hemophilia Treatment Center of CHU Sainte-Justine, and co-founder of the Quebec Reference Center for inhibitors. He is a past president of the Association of Hemophilia Clinic Directors of Canada. Dr. St-Louis’ research focus is in the fields of hemophilia and coagulation inhibitors.

Key Publications

St-Louis J, Urajnik DJ, Menard F, Cloutier S, Klaassen RJ, Ritchie B, Rivard GE, Warner M, Blanchette V, Young NL.  Generic and Disease-Specific Quality of Life Among Youth and Young Men with Hemophilia in Canada. BMC Hematol. 2016 May 5;16:13. doi: 10.1186/s12878-016-0052-x.

Charlebois J, Rivard GE and St-Louis J. Management of acquired von Willebrand Syndrome. Transfusion and Apheresis Science, 2018.  doi.org/10.1016/j.transci.2018.10. 012.

Mizrahi T, Doyon K, Dube E, Bonnefoy A, Warner M, Cloutier S, Demers C, Castilloux JF, Rivard GE, St-Louis J.  Relapse Pattern and Long-Term Outcomes in subjects with Acquired Haemophilia A.  Haemophilia, 2019. DOI: 10.1111/hae.13685

St-Louis J. Bleeding in acquired hemophilia: have we figured it out?  Blood (2020) 136 (3): 262–264.

Dubé E, Merlen C, Bonnefoy A, Gauthier J, Castilloux JF, Cloutier S, Demers C, Sabapathy CA, St-Louis J, Vezina C, Warner M, Rivard GE. A prospective surveillance study in haemophilia B patients following a population switch to recombinant factor IX (nonacog gamma). Haemophilia, 2021. Feb 8. doi: 10.1111/hae.14273

Current Positions/Chairs:

  • Member
    Hematology-Oncology Service, Hôpital Maisonneuve- Rosemont, Montreal
  • Associate Professor
    Department of Medicine, Université de Montréal
  • Co-director
    Hemophilia Treatment Center, CHU Sainte-Justine and Quebec Reference Center for Inhibitors

Key Institutions

  • Université de Montréal
    Department of Medicine
  • Hematology-Oncology Service Hôpital Maisonneuve-Rosemont
    Montréal
  • Hemophilia Comprehensive Care Centre CHU Sainte-Justine
    Montréal

Research Activities

  • 2015 - Principal Investigator and Author of Protocol. The Hemophilia Joint Health Scale v2.1 in Adult Patients: a validation study. Peer-reviewed funding by The International Prophylaxis Study Group (IPSG).
  • 2016 - Local Investigator. Changement de concentré de facteur VIII et Facteur IX au Québec: Risque de développement d’inhibiteurs. Funding by Fondation du CHU Sainte-Justine (Bayer Canada, grant for Center of Excellence in Haemostasis).
  • 2020 - Local Principal Investigator. LTE15174 – ATLAS OLE An Open-label, Longterm Safety and Efficacy Study of Fitusiran in Patients with Hemophilia A or B, with or without Inhibitory Antibodies to Factor VIII or IX. Funding by Sanofi.

Research Interests

  • Hemophilia and coagulation inhibitors

Publications

October 15, 2020

Evaluating international Haemophilia Joint Health Score (HJHS) results combined with expert opinion: Options for a shorter HJHS.

Authors
Kuijlaars IAR, van der Net J, Feldman BM, Aspdahl M, Bladen M, de Boer W, CuestaBarriuso R, Matlary RED, Funk SM, Hilliard P, John JA, Kempton CL, de Kleijn P, MancoJohnson M, Petrini P, Poonnoose P, St-Louis J, Thomas S, Timmer MA, Trakymiene SS, van Vlimmeren L, Fischer K
Citation
Haemophilia. 2020 Oct 15. doi: 10.1111/hae.14180. Epub ahead of print. PMID: 33058441.
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August 11, 2020

Reference Ranges of HJHS Scores in Healthy Adult Males without Hemophilia

Authors
St-Louis J , Abad A , Akin S , Austin S , Chowdary P , Classey S , Funk S , Hernandez G , Hilliard P, Manco-Johnson M , S. Mangles S , McLaughlin P , Nugent D , Shapiro A, Srivastava A , Tilak M , Wells A , Zourikian N , Blanchette V , Feldman BM.
Citation
Research Practice in Thrombosis and Haemostasis 2020; 4 (S1): 521, PB1032.
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July 12, 2020

Reference Ranges of HJHS Scores in Healthy Adult Males without Hemophilia

The 2020 Virtual Congress of the International Society on Thrombosis and Haemostasis (July 12 - 14, 2020)
Authors
St-Louis J , Abad A , Akin S , Austin S , Chowdary P , Classey S , Funk S , Hernandez G , Hilliard P, Manco-Johnson M , S. Mangles S , McLaughlin P , Nugent D , Shapiro A, Srivastava A , Tilak M , Wells A , Zourikian N , Blanchette V , Feldman BM
Citation
May 20, 2018

Elevated HJHS scores in healthy adult males without hemophilia

The XXXI World Federation of Hemophilia Congress (May 20 -24, 2018 – Glasgow, Scotland)
Authors
St-Louis J, Zourikian N, Funk S, Tilak M, Lobet S, Manco-Johnson M, Srivastava A, Hilliard P, Tiseo L, Abad A, Wells A, Mangles S, Blanchette V and Feldman B.
Citation
May 10, 2018

Elevated HJHS Scores in healthy adult males without hemophilia

Authors
Feldman B, Zourikian N, Funk S, Tilak M, Lobet S, Manco-Johnson M, Srivastava A, Hilliard P, Tiseo L and St-Louis J
Citation
Haemophilia 2018; 24 (S5): 176, W- FPMED01- 002
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